As Indian agent, forceful peacemaker and humanist, Maj. Neighbors had more influence over Texas' Indians than any other man of his era; came to Texas in 1836.
Her served as quartermaster in Texas Army, 1839-41. While on Texas Ranger duty in San Antonio, 1842, he was taken as a prisoner of war to Mexico by Gen. Adrian Woll and spent 18 months in Perote prison.
Began his service to the Indians in 1845. As agent for Lipan-Apache and Tonkawa tribes, he used field system of control, visiting Indian homes, learning a red man's way of life, improving living conditions, helping them to trade. He ably defended their rights, was counselor and friend, and sought new homes for them, never faltering in commitment to their safety.
As a Texas commissioner in 1850 he organized El Paso County; he was also a state representative, 1851-1852, and a Presidential elector in 1852.
Major Neighbors later became the supervising agent for all of the Indians in Texas. Frontier civilians and soldiers failed to support his Indian policies. Many became hostile. On Sept. 14, 1859, he was murdered near here by a white man as he was returning after safely removing all reservation Indians from Texas. He was buried in Belknap Cemetery (½ mi. E. of town).